Restore mitophagy is essential to prevent cardiac oxidative stress during hypertrophy
V. Peugnet, M. Chwastyniak, S. Lancel, L. Bultot, N. Fourny, O. Beseme, A. Loyens, W. Heyse, P. Amouyel, L. Bertrand, F. Pinet, E. Dubois-Deruy
This study investigates the role of mitochondrial oxidative stress in cardiac hypertrophy and evaluates the effects of two antioxidants, MitoQ and EUK 134, on cardiomyocyte function and hypertrophy.
bioRxiv · Jan 12, 2021 · PreprintCell Biology