CULTURE AND MAINTENANCE OF URINE-DERIVED, 3-DIMENSIONAL CANINE TRANSITIONAL CELL CARCINOMA ORGANOIDS
S. Thenuwara, B. Schneider, A. Mosichuk, V. Gabriel, C. Zdyrski, K. Dao, C. Iennarella-Servantez, M. Colosimo, D. Sahoo, A. Bourgois-Mochel, M. Musser, C. Johannes, J.-S. Palerme, K. Allenspach, J. P. Mochel
This study establishes urine-derived 3D canine TCC organoids as a model to study bladder cancer ex vivo, showing similar RNA biomarker expression and greater cisplatin sensitivity compared to 2D human TCC cells.
bioRxiv · Aug 24, 2021 · PreprintCancer Biology