J. P. Mochel

This study develops a virtual simulator for optimizing benazepril dosing in dogs with CHF using QSP modeling and provides a web-app for veterinary use.

This study establishes urine-derived 3D canine TCC organoids as a model to study bladder cancer ex vivo, showing similar RNA biomarker expression and greater cisplatin sensitivity compared to 2D human TCC cells.

This pilot study evaluates if prebiotics and glycosaminoglycans reduce relapse in dogs with food-responsive enteropathy on a hydrolyzed diet, finding no significant difference compared to placebo.

The paper predicts optimal dosing gaps for BEV-PEM/CIS in mice and humans to maximize efficacy while minimizing toxicity.

This study shows sacubitril/valsartan increases cGMP and reduces aldosterone in a canine RAAS activation model compared to placebo and other drugs.