A microbiota-derived metabolite instructs peripheral efferocytosis
P. H. V. Saavedra, A. Trzeciak, Z. Wang, W. S. Rojas, G. Zago, M. D. Docampo, J. G. Verter, M. R. M. van den Brink, C. D. Lucas, C. J. Anderson, A. Y. Rudensky, J. S. A. Perry
This study identifies butyrate, a microbiota-derived metabolite, as a regulator of peripheral efferocytosis, showing its ability to restore impaired phagocytic clearance in antibiotic-treated mice.
bioRxiv · Aug 17, 2022Immunology