Author

M. Doblare

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

I. Ochoa· 2 shared J. Ayensa-Jimenez· 2 shared M. Perez-Aliacar· 2 shared T. Randelovic· 2 shared A. Carrasco-Mantis· 1 shared H. Castro-Abril· 1 shared J. A. Sanz-Herrera· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

I. Ochoa

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Modelling glioblastoma resistance to temozolomide. Combination of spheroid and mathematical models to simulate cellular adaptation in vitro.

M. Perez-Aliacar, J. Ayensa-Jimenez, T. Randelovic, I. Ochoa, M. Doblare

This paper combines 3D glioblastoma spheroid experiments with mathematical models to simulate temozolomide resistance and understand cellular adaptation mechanisms.

bioRxiv · Nov 24, 2023 · PreprintCancer Biology

Modelling cell adaptation using internal variables accounting for cell plasticity in continuum mathematical biology

M. Perez-Aliacar, J. Ayensa-Jimenez, M. Doblare

The paper presents a mathematical framework to model cellular adaptation through internal variables, demonstrating its application to glioblastoma hypoxia adaptation.

bioRxiv · May 8, 2023Cancer Biology

A mechanobiological model for tumor spheroids evolution: application to glioblastoma

A. Carrasco-Mantis, H. Castro-Abril, T. Randelovic, I. Ochoa, M. Doblare, J. A. Sanz-Herrera

This paper develops a mechanobiological model to simulate glioblastoma spheroid evolution, showing that mechanical interactions and nutrient dynamics drive growth or shrinkage in different cell lines.

bioRxiv · Oct 8, 2021 · PreprintBiophysics