M. Dominguez

SMART: A Somatic Mutation Annotation and Reporting Tool for cancer genomics

SMART annotates and reports somatic mutations in cancer genomics by integrating OncoKB and other databases into a VCF-based workflow with three-tier transcript prioritisation.

TIAM1 signaling drives prostatic budding and branching phenotypes and is a potential therapeutic target for BPH

This study identifies TIAM1-RAC1 signaling as a driver of prostatic budding and branching in BPH and suggests it as a therapeutic target.

Identification of dialects and individuals of globally threatened Yellow Cardinals using neural networks

This paper uses neural networks to identify dialects and individuals of Yellow Cardinals from their songs, showing dialects exist and models can distinguish individuals with moderate accuracy.

The impact of transposable elements on tomato diversity

This study identifies transposable element insertions contributing to tomato diversity through whole-genome resequencing and GWAS.

The Notch and EGFR signaling regulate caspase inhibitor Diap1 to match supply with intestinal demand

The paper shows that Notch and EGFR signaling regulate Diap1 to control enteroblast cell death and survival in Drosophila intestine, balancing tissue renewal and tumor suppression.

Infectious Entry of Merkel Cell Polyomavirus

This study investigates the infectious entry mechanism of MCPyV, revealing caveolar/lipid raft-mediated endocytosis and endosomal membrane envelope acquisition, with endosome-to-ER trafficking as a bottleneck.