Bacteria detect neutrophils via a system that responds to hypochlorous acid and flow
I. P. Foik, S. J. Kasallis, R. Shu, S. Abbondante, M. E. Marshall, L. A. Urban, L. Duong, A. P. Huang, E. Pearlman, T. L. Downing, A. Siryaporn
This study shows Pseudomonas aeruginosa detects neutrophil-derived hypochlorous acid and uses it to upregulate the Fro operon, enhancing survival during infection.
bioRxiv · Feb 1, 2022 · PreprintMicrobiology