Author

E. Pearlman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 3 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. Marshall· 2 shared S. Abbondante· 2 shared A. P. Huang· 1 shared A. Rietsch· 1 shared A. Siryaporn· 1 shared B. A. Miller· 1 shared D. Wang· 1 shared G. Dubyak· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

M. Marshall

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The NLRP3 inflammasome selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates bacterial killing in vivo

M. Minns, T. Lima, K. Liboro, S. Abbondante, B. A. Miller, M. Marshall, J. Tran-Chau, A. Rietsch, G. Dubyak, E. Pearlman

This study shows that Pseudomonas aeruginosa uses ExoS to redirect neutrophil inflammasome signaling from NLRC4 to NLRP3, enhancing bacterial killing and reducing disease severity in mice.

bioRxiv · Apr 7, 2022 · PreprintMicrobiology

Bacteria detect neutrophils via a system that responds to hypochlorous acid and flow

I. P. Foik, S. J. Kasallis, R. Shu, S. Abbondante, M. E. Marshall, L. A. Urban, L. Duong, A. P. Huang, E. Pearlman, T. L. Downing, A. Siryaporn

This study shows Pseudomonas aeruginosa detects neutrophil-derived hypochlorous acid and uses it to upregulate the Fro operon, enhancing survival during infection.

bioRxiv · Feb 1, 2022 · PreprintMicrobiology

Control of ss-glucan exposure by the endo-1,3-glucanase Eng1 in Candida albicans modulates virulence

M. Yang, N. Solis, M. Marshall, R. A. Garleb, T. Zhou, D. Wang, M. Swidergall, E. Pearlman, S. Filler, H. Liu

This study shows that Eng1 and Ywp1 in C. albicans reduce Dectin-1 binding by masking β-glucans, thereby decreasing immune recognition and virulence.

bioRxiv · Sep 7, 2020Microbiology