Human URAT1/SLC22A12 gene promoter is regulated by 27-hydroxycholesterol through estrogen response elements
M. Matsubayashi, Y. M. Sakaguchi, Y. Sahara, H. Nanaura, S. Kikuchi, A. Ashari, L. Bui, S. Kobashigawa, M. Nakanishi, R. Nagata, T. K. Matsui, G. Kashino, M. Hasegawa, S. Takasawa, M. Eriguchi, , E. Mori
The paper identifies 27-hydroxycholesterol's role in regulating URAT1/SLC22A12 gene expression through estrogen response elements, linking cholesterol metabolism to serum uric acid levels.
bioRxiv · Nov 6, 2019 · PreprintBiochemistry