Author

M. F. Ibrahim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

J. Clayton· 1 shared J. Shen· 1 shared M. Shen· 1 shared P. Mahinthichaichan· 1 shared R. Hilgenfeld· 1 shared V. M. de Oliveira· 1 shared X. Sun· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

J. Clayton

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1 paper

Recent·Most cited

An Integrative Approach to Dissect the Drug Resistance Mechanism of the H172Y Mutation of SARS-CoV-2 Main Protease

J. Clayton, V. M. de Oliveira, M. F. Ibrahim, X. Sun, P. Mahinthichaichan, M. Shen, R. Hilgenfeld, J. Shen

This study investigates how the H172Y mutation in SARS-CoV-2 Mpro reduces nirmatrelvir efficacy using simulations, AI, and experiments, revealing structural and functional changes in the enzyme.

bioRxiv · Jul 31, 2022Biochemistry