Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter
A. Uchida, D. Murugesapillai, Y. Wang, M. F. Lodeiro, S. Prabhakar, J. Arnold, L. J. Maher, M. C. Williams, C. E. Cameron
The paper identifies sequences and structural requirements for efficient transcription from the first heavy-strand promoter in mtDNA, highlighting the role of TFAM's carboxy-terminal tail and HVR3.
bioRxiv · Apr 24, 2017Biochemistry