Comparison of Mucosal and Intramuscular Immunization against SARS-CoV-2 with Replication-Defective and Replicating Single-cycle Adenovirus Vaccines
M. A. Barry, H. Mudrick, E. McGlinch, B. Parrett, J. Hemsath, M. Barry, J. Rubin, C. Uzendu, M. Hansen, C. Erskine, V. VanKeulen, A. Drelich, C.-T. K. Tseng, C. S. Massey, M. Fida, , G. Olivier
This study compares mucosal and intramuscular immunization with replication-defective and replicating single-cycle adenovirus vaccines against SARS-CoV-2, showing that replicating vaccines generate stronger antibody responses.
bioRxiv · Apr 20, 2021 · PreprintImmunology