Oncogenic role of sFRP2 in P53-mutant osteosarcoma development via autocrine and paracrine mechanism
H. S. Kim, S. Yoo, J. M. Bernitz, Y. Yuan, A. M. Gomes, M. G. Daniel, J. Su, E. G. Demicco, J. Zhu, K. A. Moore, D.-F. Lee, I. R. Lemischka, C. Schaniel
This study identifies sFRP2 as an oncogenic driver in P53-mutant osteosarcoma through autocrine and paracrine mechanisms, showing its role in promoting tumor growth and poor survival.
bioRxiv · Jan 10, 2018Cancer Biology