Exclusion of PD-1 from the immune synapse: a novel strategy to modulate T cell function
L. Y. Hao, S. Lerrer, R. Song, M. Goeckeritz, X. Hu, A. Mor
This paper shows that anti-PD-1 antibodies enhance T cell activation by removing PD-1 from the immune synapse, suggesting a new strategy for cancer immunotherapy.
bioRxiv · Nov 16, 2023Immunology