Author

M. Gurusaran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

O. R. Davies· 3 shared B. S. Erlandsen· 1 shared H. Shibuya· 1 shared J. Zhang· 1 shared K. Zhang· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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3 shared papersBiochemistry

O. R. Davies

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3 papers

Recent·Most cited

MEILB2-BRME1 forms a V-shaped DNA clamp upon BRCA2-binding in meiotic recombination

M. Gurusaran, J. Zhang, K. Zhang, H. Shibuya, O. R. Davies

The paper reports the crystal structure of MEILB2-BRME1 complex and shows how BRCA2 binding causes it to form a V-shaped DNA clamp to facilitate meiotic recombination.

bioRxiv · Jul 4, 2023 · PreprintBiochemistry

Crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion

M. Gurusaran, B. S. Erlandsen, O. R. Davies

The paper reports the crystal structure of the SUN1-KASH6 complex, revealing an asymmetric arrangement that explains how KASH proteins can insert into the outer nuclear membrane.

bioRxiv · Jun 5, 2023Biochemistry

A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies

M. Gurusaran, O. R. Davies

This study reveals that SUN-KASH forms a 6:6 complex rather than the canonical 3:3 model, leading to a branched LINC complex network for force distribution.

bioRxiv · Mar 21, 2020Biochemistry