Epstein-Barr virus-encoded latent membrane protein 1 and B-cell growth transformation induces lipogenesis through fatty acid synthase.
M. Hulse, S. Johnson, S. Boyle, L. B. Caruso, I. Tempera
This paper shows that Epstein-Barr virus's LMP1 protein promotes B-cell transformation by inducing fatty acid synthesis and lipid droplet formation, suggesting lipogenesis inhibitors could treat LMP1-positive EBV-related cancers.
bioRxiv · Dec 15, 2019Microbiology