Identification of PIM1 substrates reveals a role for NDRG1 in prostate cancer cellular migration and invasion
R. J. Ledet, S. Ruff, Y. Wang, S. Nayak, J. A. Schneider, B. Ueberheide, S. K. Logan, M. J. Garabedian
This study identifies PIM1 substrates in prostate cancer cells, revealing that PIM1 phosphorylates NDRG1, reducing its stability and function in suppressing cell migration and invasion.
bioRxiv · Jan 21, 2020Cancer Biology