Author

M. J. Platt

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

B. G. Neel· 1 shared J. A. Simpson· 1 shared J. C. Yin· 1 shared P. H. Backx· 1 shared T. Araki· 1 shared X. Tian· 1 shared X. Wu· 1 shared

Activity by Year

2017-2017 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

B. G. Neel

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1 paper

Recent·Most cited

Cellular Interplay and Cytokine Hierarchy Cause Pathological Cardiac Hypertrophy in RAF1-Mutant Noonan Syndrome

J. C. Yin, M. J. Platt, X. Tian, X. Wu, P. H. Backx, J. A. Simpson, T. Araki, B. G. Neel

This study shows that RAF1 mutations in Noonan syndrome cause cardiac hypertrophy through cytokine signaling from endothelial cells, with TNF/IL6 as potential therapeutic targets.

bioRxiv · Mar 30, 2017Cell Biology