Drug resistance-associated mutations in Plasmodium UBP-1 disrupt ubiquitin hydrolysis
C. Smith, R. Henrici, M. Karpiyevich, M. R. Ansbro, J. Hoshizaki, G. J. van der Heden van Noort, D. B. Ascher, C. J. Sutherland, M. C. S. Lee, K. Artavanis-Tsakonas
The paper investigates mutations in Plasmodium UBP-1 linked to drug resistance and shows how these mutations affect ubiquitin hydrolysis and parasite fitness.
bioRxiv · Sep 15, 2022 · PreprintMicrobiology