Trapped in translocation: Stalling of XPD on a crosslinked DNA substrate
J. Kuper, T. Hove, S. Maidl, F. Sauer, M. Kempf, E. Greiter, H. Neitz, C. Hoebartner, C. Kisker
This study uses cryo-EM to reveal how XPD helicase stalls on interstrand crosslinked DNA, identifies functional residues, and suggests a model for NER bubble formation.
bioRxiv · Feb 20, 2024 · PreprintBiochemistry