Tracking the cells of tumor origin in breast organoids by light sheet microscopy
A. Alladin, L. Chaible, S. Reither, M. Loeschinger, M. Wachsmuth, J.-K. Heriche, C. Tischer, M. Jechlinger
The paper develops a methodology combining breast organoids and light-sheet imaging to track cell fates and finds that small groups of transformed cells form tumors while isolated cells do not.
bioRxiv · Apr 24, 2019 · PreprintCancer Biology