M. Lourenco

Phages against non-capsulated Klebsiella pneumoniae: broader host range, slower resistance

This study isolates and compares phages targeting capsule-deficient Klebsiella pneumoniae strains, finding they have broader host ranges and slower resistance emergence than phages targeting capsule-expressing strains.

The spatial heterogeneity of the gut limits bacteriophage predation leading to the coexistence of antagonist populations of bacteria and their viruses

The paper shows that spatial heterogeneity in the gut allows bacteria to coexist with their phages by providing refuge sites, challenging previous assumptions about phage-bacteria dynamics.

Rampant Reverse Evolution towards Specialization in Commensal Bacteria Colonizing the Gut

This study shows reverse evolution in gut bacteria, where a lost phenotype reappears through genetic changes, leading to coexisting generalist and specialist strains influenced by diet.