Author

M. M. Pfleiderer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:human· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Ferdigg· 1 shared A. Fraudeau· 1 shared A. Kroupova· 1 shared F. Ackle· 1 shared F. M. Boneberg· 1 shared I. Asanovic· 1 shared J. Martinez· 1 shared L. Loeff· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

A. Ferdigg

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2 papers

Recent·Most cited

Structural basis of the Integrator complex assembly and association with transcription factors

M. Razew, A. Fraudeau, M. M. Pfleiderer, W. P. Galej

This paper reports cryo-EM structures of Integrator sub-complexes and identifies ZNF655 as a TF interacting with Integrator, suggesting a role in transcription regulation.

bioRxiv · Jan 30, 2024Biochemistry

Mechanistic basis for oxidative stress protection of the human tRNA ligase complex by the oxidoreductase PYROXD1

L. Loeff, A. Kroupova, I. Asanovic, F. M. Boneberg, M. M. Pfleiderer, A. Ferdigg, F. Ackle, J. Martinez, M. Jinek

The paper identifies how PYROXD1 protects the tRNA ligase complex from oxidative stress through structural and functional interactions.

bioRxiv · Apr 6, 2023 · PreprintBiochemistry