Author

M. M. Schofield

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

J. Parreno· 2 shared A. D. Faghri· 1 shared A. Rzepski· 1 shared C. Mirack· 1 shared D. Elliott· 1 shared E. Bloom· 1 shared J. Hammerstedt· 1 shared K. L. Inguito· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

J. Parreno

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2 papers

Recent·Most cited

Targeting F-actin stress fibers to suppress the dedifferentiated phenotype in chondrocytes

M. M. Schofield, A. Rzepski, J. Hammerstedt, S. Shah, C. Mirack, J. Parreno

This study investigates how TPM3.1 and CDC42 regulate F-actin stress fibers and dedifferentiation in passaged chondrocytes, showing their roles in maintaining the dedifferentiated phenotype.

bioRxiv · Dec 8, 2023Cell Biology

Destabilization of F-actin by Mechanical Stress Deprivation or Tpm3.1 Inhibition Promotes a Pathological Phenotype in Tendon Cells

K. L. Inguito, M. M. Schofield, A. D. Faghri, E. Bloom, M. Heino, D. Elliott, J. Parreno

This study shows that F-actin destabilization by mechanical stress deprivation or Tpm3.1 inhibition in tendon cells leads to pathological gene expression changes associated with tendinosis.

bioRxiv · Feb 15, 2022 · PreprintCell Biology