The Clinical Response of Upadacitinib and Risankizumab is Associated with Reduced Inflammatory Bowel Disease Anti-TNFα Inadequate Response Mechanisms
J. Wang, M. Macoritto, H. Guay, J. W. Davis, M. C. Levesque, X. Cao
This study identifies TNF-IR up-regulated and down-regulated modules in IBD patients and shows that upadacitinib and risankizumab reduce TNF-IR up-regulated mechanisms in JAK1 responders.
bioRxiv · May 16, 2022 · PreprintImmunology