Author

M. Marazzi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Research Focus:protein structure prediction· 2 Assay:structural biology· 2 Organism:virus· 2 Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

A. Monari· 4 shared E. Bignon· 3 shared A. Terenzi· 2 shared C. Hognon· 2 shared G. Barone· 2 shared S. Grandemange· 2 shared T. Miclot· 2 shared A. France-Monerris· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 34 mutual co-author links

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4 shared papersBiophysics

A. Monari

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Author profile →

4 papers

Recent·Most cited

Hijacking of Cellular Functions by Severe Acute Respiratory Syndrome Coronavirus-2. Permeabilization and Polarization of the Host Lipid Membrane by Viroporins.

E. Bignon, M. Marazzi, A. Monari

The paper uses molecular dynamics simulations to show how SARS-CoV-2 ORF3a permeabilizes the host lipid membrane by forming a water channel, facilitating ion transport and contributing to inflammation.

bioRxiv · Apr 14, 2022Biophysics

Autophagy and evasion of immune system by SARS-CoV-2. Structural features of the Non-structural protein 6 from Wild Type and Omicron viral strains interacting with a model lipid bilayer.

E. Bignon, M. Marazzi, S. Grandemange, A. Monari

This study investigates structural changes in SARS-CoV-2 Nsp6 protein between wild-type and Omicron variants using molecular dynamics and machine learning to analyze interactions with lipid bilayers.

bioRxiv · Jan 5, 2022Biophysics

Structure and dynamics of RNA guanine quadruplexes in SARS-CoV-2 genome. Original strategies against emerging viruses

T. Miclot, C. Hognon, E. Bignon, A. Terenzi, M. Marazzi, G. Barone, A. MONARI

The paper calculates the first G4 structure of the RG-1 RNA sequence in SARS-CoV-2 genome using multiscale modeling and validates it with circular dichroism spectra, showing its stability and potential interaction with inhibitory ligands.

bioRxiv · May 20, 2021Biophysics

Role of RNA Guanine Quadruplexes in Favoring the Dimerization of SARS Unique Domain in Coronaviruses

C. Hognon, T. Miclot, C. Garcia Iriepa, A. France-Monerris, S. Grandemange, A. Terenzi, M. Marazzi, G. Barone, A. Monari

This study investigates how RNA guanine quadruplexes interact with the SARS Unique Domain using molecular dynamics simulations to understand their role in viral infection and potential therapeutic targeting.

bioRxiv · Apr 7, 2020Biophysics