KAP1 is an antiparallel dimer with a natively functional asymmetry
G. Fonti, M. Marcaida, L. Bryan, S. Traeger, A. Kalantzi, P.-Y. Helleboid, D. Demurtas, M. Tully, S. Grudinin, D. Trono, B. Fierz, M. Dal Peraro
This paper shows KAP1 forms an antiparallel dimer with a native asymmetry, which affects its SUMOylation and interaction with HP1.
bioRxiv · Feb 19, 2019Biophysics