Author

M. Metifiot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. Lapaillerie· 2 shared E. Mauro· 2 shared L. Paul· 2 shared M. Ruff· 2 shared V. Parissi· 2 shared A. Celle· 1 shared B. Lelandais· 1 shared C. Calmels· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersMicrobiology

D. Lapaillerie

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Modulation of the functional interfaces between retroviral intasomes and the human nucleosome

E. Mauro, D. Lapaillerie, C. Tumiotto, C. Charlier, F. Martins, S. Sousa, M. Metifiot, P. Weigel, K. Yamatsugu, M. Kanai, H. Lehmann, C. Richetta, J. Batisse, M. Ruff, O. Delelis, , V. Parissi

The paper develops an alphaLISA assay to study intasome-nucleosome interactions, identifies compounds that modulate this interaction, and shows their antiviral effects against PFV and HIV-1.

bioRxiv · Sep 29, 2022Microbiology

SARS-CoV-2 transmission via apical syncytia release from primary bronchial epithelia and infectivity restriction in children epithelia

G. Beucher, M.-L. Blondot, A. Celle, N. Pied, P. Recordon-Pinson, P. Esteves, M. Faure, M. Metifiot, S. Lacomme, D. Dacheaux, D. R. Robinson, G. Laengst, F. Beaufils, M.-E. Lafon, P. Berger, , H. Wodrich

This study shows that adult bronchial epithelia form infectious syncytia releasing SARS-CoV-2, while children's epithelia resist infection due to faster interferon response.

bioRxiv · May 28, 2021Microbiology

Analysis of the intrinsic chromatin binding property of HIV-1 integrase and its regulation by LEDGF/p75 using human chromosomes spreads

D. Lapaillerie, E. Mauro, B. Lelandais, G. Ferran, N. Kuschner, C. Calmels, M. Metifiot, C. Rooryck, M. Ruff, C. Zimmer, L. Paul, J. Toutain, V. Parissi

This study investigates the chromatin-binding properties of HIV-1 integrase and its regulation by LEDGF/p75 using biochemical and chromosome-binding assays.

bioRxiv · Dec 23, 2020 · PreprintMicrobiology