TFEB-Mediated Pro-inflammatory Response in Murine Macrophages Induced by Acute Alpha7 Nicotinic Receptor Activation
H. H. Honwad, M. Najibi, B. Koscso, M. Bogunovic, J. E. Irazoqui
This study shows that activating the alpha7 nicotinic receptor in macrophages triggers TFEB nuclear translocation and a pro-inflammatory gene signature without cytokine release.
bioRxiv · Jan 26, 2024Immunology