Lipopolysaccharide preconditioning augments phagocytosis of malaria-parasitized red blood cells through induced bone marrow-derived macrophages in the liver, thereby increasing the murine survival after Plasmodium yoelii infection
T. Ono, Y. Yamaguchi, H. Nakashima, M. Nakashima, T. Ishikiriyama, S. Seki, M. Kinoshita
This study shows that LPS preconditioning enhances phagocytic clearance of malaria parasites by liver macrophages, improving survival in mice infected with Plasmodium yoelii.
bioRxiv · May 22, 2020Immunology