Next-generation intranasal Covid-19 vaccine: a polymersome-based protein subunit formulation that provides robust protection against multiple variants of concern and early reduction in viral load of the upper airway in the golden Syrian hamster model
J. H. Lam, D. Shivhare, T. W. Chia, S. L. Chew, G. Sinsinbar, T. Y. Aw, S. Wong, S. Venkataraman, F. W. I. Lim, P. Vandepapeliere, M. Nallani
This paper develops an intranasal polymersome-based vaccine that provides robust protection against multiple SARS-CoV-2 variants and reduces viral load in hamsters.
bioRxiv · Feb 12, 2022 · PreprintImmunology