Evaluation of podocyte Rac-1 induced kidney disease by modulation of TRPC5
J. Reiser, O. K. Polat, E. Isaeva, K. Zhu, M. Noben, Y. Sudhini, B. Samelko, V. S. Kumar, C. Wei, M. M. Altintas, S. E. Dryer, S. Sever, A. Staruschenko
This study evaluates the role of TRPC5 in podocyte Rac-1 induced kidney disease using transgenic mice and electrophysiological experiments, finding TRPC5 inhibition does not alleviate proteinuria.
bioRxiv · May 25, 2021 · PreprintCell Biology