Cancer BiologybioRxiv
Candidate cancer driver mutations in super-enhancers and long-range chromatin interaction networks
L. Wadi, L. Uuskula-Reimand, K. Isaev…·J. Reimand
The paper identifies 41 frequently mutated regulatory elements in cancer genomes, enriched in non-coding mutations and linked to gene expression control through chromatin interactions.
DOI 10.1016/j.molcel.2019.12.027