Author

L. Wadi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. W. Reinke· 2 shared A. Murison· 1 shared A. R. Willis· 1 shared D. Thompson· 1 shared H. T. El Jarkass· 1 shared H. Tamim El Jarkass· 1 shared I. Dzneladze· 1 shared J. M. Claycomb· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

A. W. Reinke

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Author profile →

3 papers

Recent·Most cited

Genomic and phenotypic evolution of nematode-infecting microsporidia

L. Wadi, H. T. El Jarkass, T. D. Tran, N. Islah, R. J. Luallen, A. W. Reinke

This study sequenced nine nematode-infecting microsporidia genomes, revealing conserved metabolic pathways, horizontally transferred genes, and variable phenotypic traits across species.

bioRxiv · Aug 28, 2022Microbiology

A parental transcriptional response to microsporidia infection induces inherited immunity in offspring

A. R. Willis, W. Zhao, R. Sukhdeo, L. Wadi, H. Tamim El Jarkass, J. M. Claycomb, A. W. Reinke

The paper shows that parental transcriptional responses to microsporidia infection induce inherited immunity in offspring, protecting them against both microsporidia and bacterial pathogens.

bioRxiv · Oct 11, 2020Microbiology

Candidate cancer driver mutations in super-enhancers and long-range chromatin interaction networks

L. Wadi, L. Uuskula-Reimand, K. Isaev, S. Shuai, V. Huang, M. Liang, D. Thompson, Y. Li, L. Ruan, M. Paczkowska, M. Krassowski, I. Dzneladze, K. Kron, A. Murison, P. Mazrooei, , J. Reimand

The paper identifies 41 frequently mutated regulatory elements in cancer genomes, enriched in non-coding mutations and linked to gene expression control through chromatin interactions.

bioRxiv · Dec 19, 2017Cancer Biology