Actin contraction controls nuclear blebbing and rupture independent of actin confinement
M. Pho, Y. Berrada, A. Gunda, A. Lavallee, K. Chiu, A. Padam, M. L. Currey, A. D. Stephens
This study shows that actin contraction drives nuclear blebbing and rupture independently of actin confinement, with lamin B1 playing a key role in chromatin decompaction phenotypes.
bioRxiv · Dec 1, 2022Cell Biology