Metabolic and Proteomic Defects in Human Hypertrophic Cardiomyopathy
M. Previs, T. O'Leary, N. Wood, M. Morley, B. Palmer, M. LeWinter, J. Yob, F. Pagani, C. Petucci, M. S. Kim, K. Margulies, Z. Arany, D. Kelly, S. Day
This study identifies metabolic and proteomic defects in human hypertrophic cardiomyopathy, showing depletion of fatty acid derivatives and increased alternate fuel metabolites.
bioRxiv · Aug 18, 2021 · PreprintPhysiology