Short chain fatty acids enhance expression and activity of the umami taste receptor in enteroendocrine cells via a Gαi/o pathway
M. Shackley, A. J. H. Brown, E. W. Tate, G. Frost, A. C. Hanyaloglu
This study shows SCFAs enhance umami receptor expression in EECs via Gi/o signaling, improving nutrient sensing without affecting SCFA GPCRs.
bioRxiv · Jun 1, 2020Cell Biology