Amyloid beta peptides (Aβ) from Alzheimer's disease neuronal secretome induce endothelial activation in a human cerebral microvessel model
Y. J. Shin, K. M. Evitts, S. Jin, C. C. Howard, M. Sharp-Milgrom, J. E. Young, Y. Zheng
This study shows that Aβ from AD neurons activates endothelial cells, causing inflammation and thrombosis in a human brain microvessel model.
bioRxiv · Jul 27, 2022Bioengineering