Author

M. Spichty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

B. Vergier· 2 shared D. Cluet· 2 shared I. Amri· 2 shared A. Thurman· 1 shared C. Grosjean· 1 shared D. Calabresi· 1 shared J. Leault· 1 shared L. Dehau· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

B. Vergier

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Author profile →

3 papers

Recent·Most cited

Dissecting Key Multivalent Processes in Glycosidase Inhibition: Insights from Thermodynamic Modelling and Atomistic Simulations

The paper develops and validates a thermodynamic model to explain multivalent glycosidase inhibition using charged DNJ inhitopes.

bioRxiv · Nov 29, 2023 · PreprintBiochemistry

Titration of in-cellula affinities of protein-protein interactions

D. Cluet, B. Vergier, N.-P. Levy, L. Dehau, A. Thurman, I. Amri, M. Spichty

The paper introduces a genetic assay using flow cytometry to quantify protein-protein interaction affinities at the single-cell level and demonstrates its application across diverse interactions.

bioRxiv · Apr 27, 2020 · PreprintBiochemistry

A quantitative tri-fluorescent yeast two-hybrid system: from flow cytometry to in-cellula affinities

D. Cluet, I. Amri, B. Vergier, J. Leault, C. Grosjean, D. Calabresi, M. Spichty

This paper introduces a quantitative yeast two-hybrid system using fluorescent proteins and flow cytometry to measure PPI affinities in living cells.

bioRxiv · Feb 18, 2019Biochemistry