Glycation and Serum Albumin Infiltration Contribute to the Structural Degeneration of Bioprosthetic Heart Valves
A. Frasca, Y. Xue, A. P. Kossar, S. Keeney, C. Rock, A. Zakharchenko, M. Streeter, R. C. Gorman, J. B. Grau, I. George, J. E. Bavaria, A. Krieger, D. Spiegel, R. J. Levy, G. Ferrari
This study shows glycation and serum albumin infiltration contribute to structural degeneration of bioprosthetic heart valves through mechanisms observed in both clinical samples and in vitro models.
bioRxiv · Feb 14, 2020Bioengineering