Author

C. Rock

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1 Organism:rat· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Krieger· 2 shared A. Zakharchenko· 2 shared G. Ferrari· 2 shared S. Keeney· 2 shared A. Frasca· 1 shared A. P. Kossar· 1 shared C. D. Johnston· 1 shared D. L. Weller· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBiochemistry

A. Krieger

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Inhibition of advanced glycation end product formation and serum protein infiltration in bioprosthetic heart valve leaflets: Investigations of anti-glycation agents.

A. Zakharchenko, C. Rock, T. Thomas, S. Keeney, E. Hall, H. Takano, A. Krieger, G. Ferrari, R. Levy

This study investigates anti-AGE agents' effects on AGE and serum protein infiltration in bioprosthetic heart valves using in vitro and in vivo models, finding that PYR significantly inhibits AGE and serum albumin accumulation.

bioRxiv · Feb 28, 2022 · PreprintBiochemistry

A bacterial pan-genome makes gene essentiality strain-dependent and evolvable

F. Rosconi, E. Rudmann, J. Li, D. Surujon, J. Anthony, M. Frank, D. S. Jones, C. Rock, J. W. Rosch, C. D. Johnston, T. van Opijnen

The paper investigates how a bacterial pan-genome affects gene essentiality and shows that essential genes can evolve to become non-essential through genetic changes and mechanisms like functional redundancy and pathway rewiring.

bioRxiv · Feb 8, 2022Microbiology

Glycation and Serum Albumin Infiltration Contribute to the Structural Degeneration of Bioprosthetic Heart Valves

A. Frasca, Y. Xue, A. P. Kossar, S. Keeney, C. Rock, A. Zakharchenko, M. Streeter, R. C. Gorman, J. B. Grau, I. George, J. E. Bavaria, A. Krieger, D. Spiegel, R. J. Levy, G. Ferrari

This study shows glycation and serum albumin infiltration contribute to structural degeneration of bioprosthetic heart valves through mechanisms observed in both clinical samples and in vitro models.

bioRxiv · Feb 14, 2020Bioengineering

Complex interactions between weather, and microbial and physiochemical water quality impact the likelihood of detecting foodborne pathogens in agricultural water

D. L. Weller, N. Brassill, C. Rock, R. Ivanek, E. Mudrak, S. Roof, E. Ganda, M. Wiedmann

This study examines how environmental factors and microbial indicators influence pathogen detection in agricultural water, finding that E. coli levels alone are not sufficient to predict food safety risks.

bioRxiv · Jan 2, 2020Microbiology