M. Tripathy

Using Packing Defects in Heterogeneous Biological Membrane as a Lens to Explore Protein Localization Propensity and Small Molecule Permeability

The paper uses computer simulations to study how membrane heterogeneity affects protein localization and small molecule permeability by analyzing packing defects and local membrane order.

Protein as evolvable functionally-constrained amorphous matter

The paper models proteins as amorphous materials using graph representations to study functional features and their evolutionary emergence.

How does temperature affect the dynamics of SARS-CoV-2 M proteins? Insights from Molecular Dynamics Simulations

This study uses molecular dynamics simulations to investigate how temperature affects the dynamics of SARS-CoV-2 M proteins and their interactions with membranes, finding a non-monotonic temperature-dependent behavior.

3D Packing Defects in Lipid Membrane as a Function of Membrane Order

The paper introduces a 3D algorithm to calculate lipid membrane packing defects and shows that defects are shallower and smaller in liquid-ordered phases compared to liquid-disordered and mixed phases.

Characterizing the Liquid-liquid Phase Co-existence in Biomembrane: Insights from Local Non-affine Deformation and Topological Rearrangements

This study characterizes liquid-liquid phase coexistence in biomembranes using non-affine deformation and topological rearrangements, identifying ordered and disordered phases without prior lipid knowledge.