Tropomyosin 1 deficiency facilitates cell state transitions and enhances hemogenic endothelial cell specification during hematopoiesis
M. Wilken, G. Fonar, C. Nations, G. Pavani, J. Gariffalou, J. Tober, L. F. Bennett, J. A. Maguire, A. Gagne, N. Okoli, P. Gadue, S. Chou, N. A. Speck, D. French, C. S. Thom
This study shows TPM1 deficiency promotes cell state transitions and enhances hemogenic endothelial cell specification during hematopoiesis in both human and mouse models.
bioRxiv · Sep 1, 2023Cell Biology