Diverse Phosphoserine Phosphatases Exhibit Maximum Activity at an Intermediate Binding Affinity in Accord with the Sabatier Principle of Catalysis
Y. Chiba, H. Ooka, M. Wintzer, N. Tsunematsu, T. Suzuki, N. Dohmae, R. Nakamura
This paper shows that phosphoserine phosphatases exhibit maximum activity at an intermediate binding affinity, supporting the Sabatier principle of catalysis when considering both Km and the product release rate constant.
bioRxiv · Mar 10, 2023 · PreprintBiochemistry