ImmunologybioRxiv
An In Vivo Method for Diversifying the Functions of Therapeutic Antibodies
M. Tian, H.-L. Cheng, M. T. Kimble…·F. W. Alt
This paper develops a method to diversify therapeutic antibodies by mimicking natural B cell processes in mice, resulting in new antibodies with altered functions.
DOI 10.1073/pnas.2025596118