Author

K. McGovern

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. Cantor· 2 shared F. W. Alt· 2 shared H.-L. Cheng· 2 shared M. Dao· 2 shared M. T. Kimble· 2 shared M. Tian· 2 shared P. Waddicor· 2 shared Y. Chen· 2 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

E. Cantor

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2 papers

Recent·Most cited

An In Vivo Method for Diversifying the Functions of Therapeutic Antibodies

M. Tian, H.-L. Cheng, M. T. Kimble, K. McGovern, P. Waddicor, Y. Chen, E. Cantor, M. Qiu, M.-E. Tuchel, M. Dao, F. W. Alt

This paper develops a method to diversify therapeutic antibodies by mimicking natural B cell processes in mice, resulting in new antibodies with altered functions.

bioRxiv · Dec 12, 2020Immunology

Conditional Antibody Expression to Avoid Central B Cell Deletion in a Humanized HIV-1 Vaccine Mouse Models

M. Tian, K. McGovern, H.-L. Cheng, P. Waddicor, L. Rieble, M. T. Kimble, M. Dao, Y. Chen, E. Cantor, N. Manfredonia, R. Judson, A. Chapdelaine-Williams, D. W. Cain, B. F. Haynes, F. W. Alt

This paper develops a conditional expression strategy to enable mature B cell expression of bnAb precursors in transgenic mice, overcoming developmental blocks caused by bnAb properties.

bioRxiv · Jan 3, 2020Immunology