Pharmacology & ToxicologybioRxivPreprint
Pharmacological activation of constitutive androstane receptor induces female-specific modulation of hepatic metabolism
M. Huillet, F. Lasserre, M.-P. Gratacap…·S. Ellero-Simatos
This study shows that pharmacological activation of CAR leads to sex-specific changes in hepatic metabolism and drug-induced liver injury in mice.
DOI 10.1101/2023.04.17.537169