Author

C. Canlet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Biochemistry· 1 Cell Biology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 4 Organism:mouse· 4 Research Focus:differential expression· 3 Research Focus:host-pathogen & immune response· 3 Assay:metabolomics· 3 Research Focus:gene regulatory network inference· 2 Research Focus:metabolism & bioenergetics· 2

Frequent Co-Authors

A. Fougerat· 4 shared A. Polizzi· 4 shared C. Naylies· 4 shared F. Lasserre· 4 shared H. Guillou· 4 shared N. Loiseau· 4 shared S. Ellero-Simatos· 4 shared Y. Lippi· 4 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersPharmacology & Toxicology

A. Fougerat

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

p110alpha-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD

M. Regnier, A. Polizzi, T. Fougeray, A. Fougerat, P. Perrier, K. Anderson, Y. Lippi, S. Smati, C. Lukowicz, F. Lasserre, E. Fouche, M. Huillet, C. Rives, B. Tramunt, C. Naylies, , H. Guillou

This study investigates the role of p110alpha in hepatocyte signaling, showing its critical impact on liver gene expression and its rewiring in MASLD.

bioRxiv · Jan 9, 2024 · PreprintCell Biology

Pharmacological activation of constitutive androstane receptor induces female-specific modulation of hepatic metabolism

M. Huillet, F. Lasserre, M.-P. Gratacap, B. Engelmann, J. Bruse, A. Polizzi, T. Fougeray, C. M. P. Martin, C. Rives, A. Fougerat, C. Naylies, Y. Lippi, G. Garcia, E. Rousseau-Bacquie, C. Canlet, , S. Ellero-Simatos

This study shows that pharmacological activation of CAR leads to sex-specific changes in hepatic metabolism and drug-induced liver injury in mice.

bioRxiv · Apr 17, 2023 · PreprintPharmacology & Toxicology

Obesity promotes Fumonisin B1 toxicity and induces hepatitis

L. Dopavogui, M. Regnier, A. Polizzi, Q. Ponchon, S. Smati, W. Klement, F. Lasserre, C. Lukowicz, Y. Lippi, A. Fougerat, J. Bertrand-Michel, C. Naylies, C. Canlet, L. Debrauwer, L. Gamet-Payrastre, , N. Loiseau

This study shows that obesity increases susceptibility to fumonisin B1 toxicity, leading to gut dysbiosis and severe liver inflammation.

bioRxiv · Jul 22, 2022 · PreprintPharmacology & Toxicology

Slightly different metabolomic profiles are associated with high or low weights duck foie gras

H. REMIGNON, B. LO, N. Marty-Gasset, H. Manse, C. Canlet, R. Domitile

This study compares metabolomic profiles of high and low weight duck livers to identify metabolic differences associated with fatty liver weight variation during overfeeding.

bioRxiv · Aug 4, 2021 · PreprintBiochemistry

Functional maturation of the gut microbiota at weaning is influenced by maternal environment in piglets

M. Beaumont, L. Cauquil, A. Bertide, I. Ahn, C. Barilly, L. Gill, C. Canlet, O. Zemb, G. Pascal, A. Samsom, S. Combes

This study shows that weaning alters gut microbiota function in piglets, with changes influenced by maternal environment.

bioRxiv · Apr 2, 2020 · PreprintMicrobiology

Hepatocyte-specific deletion of Pparα promotes NASH in the context of obesity

M. Regnier, A. Polizzi, S. Smati, C. Lukowicz, A. Fougerat, Y. Lippi, E. Fouche, F. Lasserre, C. Naylies, C. Betoulieres, V. Barquissau, E. Mouisel, J. Bertrand-Michel, A. Batut, T. Al Saati, , A. Montagner

This study shows that deleting Ppar in hepatocytes promotes NASH in obese mice without glucose intolerance, highlighting the role of extra-hepatocyte PPAR in metabolic responses to HFD.

bioRxiv · Jan 18, 2019 · PreprintPathology