Author

Man Chu

Soochow University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Beibei XuiD· 2 shared Kai DingiD· 2 shared Xudong CaoiD· 2 shared Yulong HeiD· 2 shared Bin Shen· 1 shared Dengwen Zhu· 1 shared Fei ZhouiD· 1 shared Ganqiang LiuiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersDevelopmental Biology

Beibei XuORCID

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2 papers

Recent·Most cited

Lymphatics unload VEGFR3 in response to the alteration of VEGFR2-mediated transcriptional programs

T J Li, Xudong Cao, Fei Zhou, X G Li, W X, Xiuyan Zhang, H Zhong, Beibei Xu, Man Chu, Xiwen Jia, Kai Ding, Xin Shen, Yahui Liu, Yun Zhao, Zhen Zhang, , Yulong He

This study shows that VEGFR2 is essential for maintaining lymphatic endothelial identity and its loss alters transcriptional programs, reducing VEGFR3-mediated lymphangiogenesis.

Angiogenesis · Jul 26, 2026Peer-reviewedDevelopmental Biology

Endothelial TIE1 restricts angiogenic sprouting to coordinate vein assembly in synergy with its homologue TIE2

Xudong Cao, Taotao Li, Beibei Xu, Kai Ding, Weimin Li, Bin Shen, Man Chu, Dengwen Zhu, Li Rui, Zhi Shang, Xiao Li, Yinyin Wang, Shuyu Zheng, Kari K. Alitalo, Ganqiang Liu, , Yulong He

This study investigates the role of TIE1 and its interaction with TIE2 in venous development, finding that TIE1 restricts angiogenic sprouting to coordinate vein formation.

Arteriosclerosis Thrombosis and Vascular Biology · Jun 15, 2023Peer-reviewedDevelopmental Biology