Molecular BiologyThe EMBO JournalPeer-reviewed
Uncoupling from transcription protects polyadenylation site cleavage from inhibition by DNA damage
Rym Sfaxi, Biswendu Biswas, Galina Boldina…·Stéphan Vagner
The paper shows that post-transcriptional PAS cleavage of p53 pre-mRNA allows it to escape DNA damage inhibition, and identifies other DDR-related pre-mRNAs with similar mechanisms.
4 citations